O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport.
The serine-rich repeat (SRR) glycoproteins are a family of adhesins found in many Gram-positive bacteria.Expression of the SRR adhesins has been linked to virulence for a variety of infections, including streptococcal endocarditis.The SRR preproteins undergo intracellular glycosylation, followed by export via the accessory Sec (aSec) system.This sp